Department

Department may refer to:

Government and military

DEPT

DEPT may refer to:

DEPT (medicine)

Directed Enzyme Prodrug Therapy (DEPT) uses enzymes artificially introduced into the body to convert Prodrugs, which have no or poor biological activity, to the active form in the desired location within the body. Many chemotherapy drugs for cancer lack tumour specificity and the doses required to reach therapeutic levels in the tumour are often toxic to other tissues. DEPT strategies are an experimental method of reducing the systemic toxicity of a drug, by achieving high levels of the active drug only at the desired site. This article describes the variations of DEPT technology.

Antibody-directed enzyme prodrug therapy (ADEPT)

ADEPT is a strategy to overcome the problems of lack of tumor selectivity. An antibody designed/developed against a tumor antigen is linked to an enzyme and injected to the blood, resulting in selective binding of the enzyme in the tumor. When the discrimination between tumor and normal tissue enzyme levels is sufficient, a prodrug is administrated into the blood circulation, which is converted to an active cytotoxic drug by the enzyme, only within the tumor. Selectivity is achieved by the tumor specificity of the antibody and by delaying prodrug administration until there is a large differential between tumor and normal tissue enzyme levels.

Tourism

Tourism is travel for pleasure; also the theory and practice of touring, the business of attracting, accommodating, and entertaining tourists, and the business of operating tours. Tourism may be international, or within the traveler's country. The World Tourism Organization defines tourism more generally, in terms which go "beyond the common perception of tourism as being limited to holiday activity only ", as people "traveling to and staying in places outside their usual environment for not more than one consecutive year for leisure, business and other purposes".

Tourism can be domestic or international, and international tourism has both incoming and outgoing implications on a country's balance of payments. Today, tourism is a major source of income for many countries, and affects the economy of both the source and host countries, in some cases being of vital importance.

Tourism suffered as a result of a strong economic slowdown of the late-2000s recession, between the second half of 2008 and the end of 2009, and the outbreak of the H1N1 influenza virus, but slowly recovered. International tourism receipts (the travel item in the balance of payments) grew to US$1.03 trillion (€740 billion) in 2011, corresponding to an increase in real terms of 3.8% from 2010. International tourist arrivals surpassed the milestone of 1 billion tourists globally for the first time in 2012, the same year in which China became the largest spender in international tourism globally with US$102 billion, surpassing Germany and United States. China and emerging markets such as Russia and Brazil had significantly increased their spending over the previous decade.

Tourism (Leftfield album)

Tourism is a live album by electronica musicians Leftfield released in March 2012 with an accompanying DVD with visuals from their latest tour, made by the visual artist collective Ne1co. The album was recorded between 5th - 18th March 2011 at The Future Music Festival across Australia and at The Enmore Theatre, Sydney and The Palace, Melbourne.

Track listing

References

Tourism (Roxette album)

Tourism: Songs from Studios, Stages, Hotelrooms, and other strange Places is the fourth album by Swedish pop duo Roxette. Released on 28 August 1992, it was recorded mostly during their Join the Joyride world tour and is often mistaken for being a live album. In fact, it is a mixture of live and studio tracks.

Album information

Four live tracks were included in the album, "The Look", "It Must Have Been Love", "Things Will Never Be the Same" and "Joyride". While "It Must Have Been Love" didn't appear on a Roxette album until their greatest hits album Don't Bore Us, Get to the Chorus!, the other three songs did appear on Look Sharp! and Joyride.

Another three songs were also released before, "So Far Away" was included on their 1986 debut album Pearls of Passion, "Come Back (Before You Leave)" was originally the B-side for the "Joyride" single, while "Silver Blue" originally appeared as a demo version as the B-side for "The Look" single. "Here Comes the Weekend", the album's 11th track, featured some improvisation. As the song was recorded in a hotelroom, a Samsonite suitcase was used instead of drums.